These 6 kinds of drugs should not be eaten indiscriminately. Some foreign and domestic drugs have been banned, and many people still use them as standing drugs.

"Why can't you sell me medicine?"

Aunt Wang was very helpless. Her granddaughter had a fever, so she thought of going to the pharmacy to buy some anti-fever artifact "An Naigen". However, the clerk had to register physical information and said that it could not be given to anyone under the age of 18.

Aunt Wang recalled that in the past, anyone at home who had a fever would take Analgin, which was cheap and easy to use. Why can't they be bought in pharmacies now? Aunt Wang thinks it must be cheap, so pharmacies are not willing to sell them...

1. These 6 kinds of drugs have been "banned", do you still use them as standing drugs?

Some common backup drugs are easy to use and effective, but they may have been "banned" in some regions or countries, such as the following 6 drugs:

1. Compound Licorice Tablets

Compound Licorice Tablets is a compound preparation of Chinese and Western medicines for relieving cough , and its ingredients contain cocaine, also known as cocaine . In 2014, someone brought 16 bottles of compound licorice tablets to the United States. They were considered to be carrying contraband, and they were ordered not to enter the country for five years.

China's National Medical Products Administration issued a notice in July 2013 requiring drug retail companies to set up special counters for compound licorice tablets, which are managed and registered by special personnel .

In March 2020, the State Drug Administration revised the drug insert of compound licorice tablets, pointing out that compound licorice tablets contain opioids , which will affect urine morphine detection during the medication and 3 to 4 days after drug withdrawal; if Long-term use may cause dependence ; may cause hypokalemia.

2. Ribavirin

Ribavirin, also known as ribavirin, is mainly used to treat severe lower respiratory tract infections caused by respiratory syncytial virus infection.

Ribavirin mainly includes injections, aerosols, nasal drops, oral preparations, etc. in China, and the clinical abuse is relatively serious. In some countries in Europe and the United States, injections are not approved.

In 2006, the State Drug Administration warned about the safety of ribavirin. A large number of studies have shown that ribavirin has obvious teratogenic and embryo-killing toxic effects through animal experiments.

In addition, the main toxicity of ribavirin is hemolytic anemia, which may lead to decreased red blood cells, decreased hemoglobin, and decreased white blood cells, and 10% of patients will also be accompanied by cardiopulmonary side effects.

3. Analgin

Analgin is an antipyretic and analgesic drug belonging to the pyrazolone class. It became a commonly used antipyretic and analgesic drug in clinical practice in the 1920s, but it attracted widespread attention in the 1970s due to serious adverse reactions. The FDA officially banned Analgin in 1977.

In China, policies to restrict the use of analgin have also been issued many times, and in 1982, the former Ministry of Health eliminated compound analgin tablets. use.

Although there are still some Analgin drugs in circulation that have not yet cancelled the production approval number, in 2020, the State Food and Drug Administration revised the instructions for Analgin tablets, adding warning words to remind that it may cause blood system problems. Serious adverse reactions and may lead to severe allergic reactions , only in the case of acute and serious illness and no other medicine can replace it, contraindicated in children under 18 years old.

4. Pidotimod

Pidotimod is a synthetic immune booster that used to be a best-selling drug in pediatrics, but there is still a lack of high-quality and reliable clinical research.

In China, in March 2018, the State Drug Administration revised the instructions for various preparations of pidotimod, and subsequently issued a notice requiring the manufacturers of pidotimod preparations to start clinical effectiveness trials as soon as possible, and to obtain the results within three years. Evaluation results.

5. Domperidone

Domperidone is a peripheral dopamine receptor blocker that can directly act on the gastrointestinal wall, enhance gastric motility, inhibit vomiting, nausea, and prevent bile reflux. It is often used as a digestive aid in China for a long time.

The US FDA has not approved any indication for domperidone, and many European countries have approved it for sale.

In 2016, China's State Drug Administration revised the instructions for domperidone preparations, clarifying that taking domperidone in some patients may increase the risk of severe ventricular arrhythmia or even sudden cardiac death , and it is forbidden to take domperidone with erythromycin, Ketoconazole oral preparations and other drugs are used in combination.

6. Phenolphthalein tablets

Phenolphthalein is an irritating "laxative", which is often used by many people to treat constipation or lose weight. It is cheap, and has a strong and fast effect on constipation. It is often used clinically to treat intractable constipation or do colonoscopy. Intestinal cleansing before examination.

However, phenolphthalein tablets contain irritating ingredients, and long-term use will lead to drug accumulation, irritation and damage to the intestinal mucosa, which may lead to colon melanosis in severe cases and increase the risk of intestinal cancer.

On January 14, 2021, the China National Medical Products Administration announced to stop the production, sales and use of phenolphthalein tablets and phenolphthalein lozenges in China , and to cancel the registration certificate of the drug.

2. Taking medicines healthily and safely, one of these steps is indispensable

There are also university questions about taking medicine. If you want to take medicine safely and healthily, you must carefully read the instructions and understand these 5 information:

First of all, when buying medicines, you should look for the OTC logo in the upper right corner of the medicine box. OTC medicines are over-the-counter medicines, and they can be divided into category A with red background and category B with green background. Green has a higher safety factor .

Secondly, all domestic regular medicines or health care medicines have the words "National Medicine Zhunzi" on the instructions. If the instructions are marked with "National Food Health" or "Health Food Health", it means that it is only a health food, not a health drug. . "Wei Yao Jian Zi" has been abolished, do not take this medicine.

In addition, pay attention to the shelf life of the drug. Once the drug expires or deteriorates, it will not only cause the drug to fail, but may also cause toxic reactions. So, be careful not to take medicines that are close to their expiration date and medicines that have changed in appearance.

It also depends on the contraindicated groups . "Use with caution" is a primary warning, while "do not use" and "disabled" are more severe warnings. If you belong to a contraindicated group, it may increase the occurrence of adverse reactions. You must communicate with your doctor to confirm.

Finally, take it according to the dose and time. Taking medicine before meals generally refers to 15-30 minutes before meals, after meals generally refers to 15-30 minutes after meals, and fasting generally refers to 1-2 hours before meals.

3. Effervescent tablets, sustained-release tablets, chewable tablets, the correct posture for taking medicine is different

The dosage form of the drug is different, and the way of taking it is also different. For these special dosage forms below, pay attention to these separately.

Effervescent tablets must not be put directly into the mouth or taken with water. It is recommended to soak in 100~150 ml of warm water first, and drink it after the bubbles disappear completely.

Sustained-release tablets should usually be swallowed whole, not chewed or broken apart.

Chewable tablets , put them in the mouth and chew them thoroughly before swallowing or take them with a small amount of warm water.

Sublingual lozenges, which are usually ineffective when swallowed directly, should be held under the tongue for about five minutes, or until completely dissolved.

In short, no matter what medicine you take, you must read the instructions carefully, it is best to take it under the guidance of a doctor, and do not abuse drugs.

References:

[1] When will "Annal Recent Films" be phased out? 》.China Pharmacy.2022-05-15

[2] "On the Internet, "Many people are still using these 6 drugs that have been banned." Is it true? 》. Center for Drug Evaluation. 2020-04-07

[3] "Completely discontinued! Is this commonly used drug a carcinogenic risk? Please throw away any at home...". Popular Science China. 2021-01-21

Reproduction is prohibited without the author's permission