What are the benefits of a few dollars of vitamin E? You may reap 3 benefits, but be careful not to eat too much
Recently, Xiaojiu received a private letter from a netizen, she asked:
"I'm only 35 years old this year, but my face has already started to grow melasma! Xiao Jiu, I heard that vitamin E can remove freckles. I would like to ask if it is useful to go to the pharmacy to buy vitamin E tablets to take? Too much vitamin E is good for the body. Will there be any impact?"
In fact, fans often ask Xiaojiu about taking vitamin E. Many people think that vitamin E can anti-aging, so what are the effects of vitamin E? What precautions should be taken when taking vitamin E? This time, Xiao Jiu will come to tell you in detail.
1. Research finds: vitamin E supplementation may enhance the effect of immunotherapy
In April, a study published in Cancer Discovery, a top journal in oncology, found that vitamin E enhances immunotherapy responses in cancer patients.
Combining regression analysis of clinical records and in-depth laboratory studies, the researchers found that vitamin E can directly target the DC intrinsic checkpoint SHP1, thereby reinvigorating DC antigen presentation and initiating T cell antitumor immune responses.
That said, vitamin E may improve immune checkpoint therapy in cancer patients.
In addition, there are claims that vitamin E helps prevent cancer, is it true?
A study in the Journal of the National Cancer Institute found that vitamin E supplementation may reduce the risk of cancer, but only in individuals who carry specific alleles of the catechol-O-methyltransferase (COMT) gene .
The researchers found that after taking vitamin E, the total cancer incidence of met/met individuals was significantly reduced, and the total cancer incidence of val/val individuals, including lung cancer, breast cancer, uterine cancer, lymphoma and leukemia, was significantly reduced. increased, but had no effect in val-met individuals.
In addition, another study published in the "Journal of the American Medical Association" pointed out that taking too much vitamin E (400 international units per day) increases the risk of prostate cancer in men .
Therefore, vitamin E cannot be supplemented casually or excessively, and random supplementation may increase the risk of disease.
It should be noted that the following three types of people are not suitable for vitamin E supplementation:
Cancer radiotherapy patients : Because vitamin E supplementation may reduce the efficacy of radiotherapy.
Breast cancer patients : Because vitamin E is found in some edible oils, eggs, meat and nuts, excessive intake of fat will increase the risk of breast cancer recurrence.
General healthy population : Vitamin E supplementation is not recommended for disease prevention.
2. Vitamin E is taken orally for anti-aging, and can be used externally to lighten spots?
Vitamin E has always been known as a beauty ingredient. Many people believe that oral vitamin E supplements can delay aging, and applying vitamin E to the face can lighten spots and improve skin texture. Does vitamin E really fight aging and fade spots?
In daily life, air pollution, water pollution, ultraviolet radiation and excessive stress may accelerate aging and cause illness, and people's skin will also deteriorate due to this, such as wrinkles, sagging of the face, and loose skin.
Vitamin E can inhibit and eliminate free radicals and protect cells and tissues from free radical damage . Therefore, vitamin E has antioxidant and anti-aging effects.
However, people who are not deficient in vitamin E do not need additional supplements. Generally, they can get enough vitamin E as long as they have a healthy diet.
As for the effect of "external use can lighten spots", vitamin E does not.
External application of vitamin E can effectively prevent skin photoaging caused by ultraviolet radiation, and can also reduce acute inflammatory reactions such as erythema and edema caused by sun exposure.
However, the effect of vitamin E on freckle removal and whitening is not accurate at present. In addition, the stability of vitamin E is extremely low, and it is easily oxidized . It is often used in combination with other reducing substances such as vitamin C.
It should be noted that you should never use oral vitamin E on your face every day , because oral vitamin E capsules are more than 90% of the ingredients for convenience of taking and gastrointestinal absorption, and these oily substances cannot be absorbed by the skin. of.
Applying vitamin E to oily and acne-prone skin will add oil to the skin, clog pores, and cause more acne.
If you take vitamin E correctly, you may reap the following benefits:
1. Anti-aging
Vitamin E can protect the fatty acids on the cell membrane from being oxidized, thereby keeping the cell membrane active and metabolism normal, slowing down the rate of cell aging, and people's aging will naturally be delayed.
2. Improve immunity
Vitamin E can regulate and enhance immune function. For example, regular supplementation of vitamin E in patients with rheumatoid arthritis can effectively improve the uncomfortable symptoms of joint stiffness and pain.
3. Helps hormone secretion
Before going to bed at night, taking an appropriate amount of vitamin E can promote the secretion of sex hormones in the body. For men, it can increase sperm count and its survival rate, and for women, it can increase the concentration of estrogen, thereby improving fertility.
3. Do not abuse vitamin E, it is not harmful
Although vitamin E has many benefits, if it is not used properly, it may also bring many harm to the body.
Long-term daily intake of 400-800 mg/day of vitamin E may cause symptoms such as headache, dizziness, blurred vision, nausea, abdominal pain, diarrhea and breast enlargement;
Long-term use of vitamin E > 800 mg/day may cause bleeding tendency in patients with vitamin K deficiency, changes in endocrine metabolism, immune mechanism, and increase thrombophlebitis, thromboembolism and heart failure risk of other diseases.
Those who may really need additional vitamin E supplementation are those with severe partial eclipse habits, eating disorders, or people with certain vitamin deficiency diseases .
In addition to oral supplements, vitamin E can be supplemented through the diet.
Vitamin E is found in vegetable oils, nuts, seeds, fruits and vegetables such as wheat germ oil, soybean oil, flax oil, sunflower seeds, almonds, peanuts, beets, kale, spinach, pumpkin, lamb liver, yuba, mulberries, walnuts, Cereal products, etc.
Vitamin E is not only an essential vitamin, but also the primary antioxidant, important for vision, reproduction, blood, brain and skin health.
When there is too little or too much vitamin E in the body, it will have a series of adverse effects on the body. However, before supplementing with vitamin E, you should consult a professional doctor and take it according to the dosage under the guidance of your doctor.
References:
[1]Yuan X， Duan Y， Xiao Y， Sun K， Qi Y， Zhang Y et al. Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1. Cancer Discovery. 2022;12(7)：1742-1759.
[2]Hall K， Buring J， Mukamal K， Vinayaga Moorthy M， Wayne P， Kaptchuk T et al. COMT and Alpha-Tocopherol Effects in Cancer Prevention： Gene-Supplement Interactions in Two Randomized Clinical Trials. JNCI： Journal of the National Cancer Institute. 2019;111(7)：684-694.
[3] " Vitamins can't be supplemented with excessive vitamin E or cause cancer ". Life Times. 2019-08-11
Reproduction is prohibited without the author's permission