Link between body weight and Alzheimer's discovered? This has the best BMI and lower risk of dementia
If Your Memory Was Stolen At 48....
Sister Liang was sent to the psychiatric department of a certain hospital. Her family members said that she suspected it was Alzheimer's disease.
Sister Liang's husband said that he lost the keys of the house several times, and now they hang the keys directly around her neck. I think the washed clothes have not been washed, and I don’t remember to take them out to dry after washing. I usually forget to add salt or repeat it many times when I cook.
The most serious thing is that half a year ago, half of the people left after cooking, but they forgot, and the kitchen started to smoke and catch fire. Fortunately, it was extinguished in time to avoid a catastrophe.
Go to the local hospital for examination and found that there is already brain atrophy , suspected senile dementia.
Then the family took Sister Liang to the provincial hospital for further examination. During the physical examination, the doctor found that Sister Liang's condition was very bad: she was not concentrating, often answered irrelevant questions, her memory and comprehension ability were lower than ordinary people, and the MMSE examination score was only 14 , which was in line with the standard. Diagnosis of clinical dementia.
The MRI results also surprised the doctor. Under normal circumstances, Sister Liang's brain should be full, but at this time it showed that the brain parenchyma was atrophied with deep sulci, and the hippocampus was also atrophied.
The doctor said that although Sister Liang is 48 years old, at this time she is the same as an old man in her 70s .
1. Maintain this number of body mass index, the lowest risk of dementia
Obesity is one of the risk factors for Alzheimer's, but do you know what the exact relationship is?
The clinical team of Professor Yu Jintai, Department of Neurology, Huashan Hospital Affiliated to Fudan University, and the team of Professor Feng Jianfeng/Cheng Wei, Institute of Brain-Inspired Intelligence, Fudan University, jointly conducted a study to confirm the relationship and underlying mechanism between obesity and dementia risk. The results Published in MolecularPsychiatry, the top journal in the medical field.
The average follow-up time of this study was 8.71 years, and a follow-up investigation was conducted on 322,336 non-demented people aged 50-73. It was found that:
• 1.18-fold increased risk of dementia in very low birth weight compared with normal birth weight
• Obese childhood size was associated with an 18% increased risk of dementia compared with average body size
• The optimal BMI is 29.2kg/m² for men and 28.5kg/m² for women . A U-shaped relationship between body mass index (BMI) and dementia risk in adults.
The conclusion of this study is that low birth weight , obesity in childhood, and being overweight or underweight in adulthood will significantly affect the risk of dementia , so it is especially important to develop weight control from an early age!
2. Dementia may be latent for 20 years, don't let go of the body's reminder
The family members discovered that Sister Liang’s abnormality had occurred in the past two years, but the doctor believed that Sister Liang had been ill for at least 5 years .
Although the process of dementia is slow, the incubation period can range from a few months to several years, and some even 20 years. Therefore, early detection of dementia is especially important, and the top ten symptoms of dementia cannot be ignored!
Difficulty dealing with familiar things
Memory continues to decline, which has affected daily life
Declining ability to judge
Difficulties in expressing language
Often put things in the wrong place
Gradually become confused about who, time, and place
Personality changes
Emotional instability
Decreased ability to understand and organize things
Loss of initiative to do things
Of course, you don’t need to worry too much. Although brain cells will degenerate to varying degrees after entering old age, most of the surviving brain cells have functions and have certain compensatory functions, which can help us maintain normal mental activities.
Relevant clinical research data in recent years have shown that the degeneration of brain cells will not gradually stop until about 90 years old, and only 4% to 5% of the elderly will suffer from dementia. The vast majority of the elderly are actually relatively healthy in brain function , life is not only not affected, and even has a certain ability to study and work.
Three, two kinds of eating habits, or increase the risk of dementia
We know that dementia is not the result of old age, in fact, some habits may bring us one step closer to dementia.
1. Skip breakfast
A study published in the "Japanese Journal of Health and Social Service Human Sciences" conducted a 6-year follow-up survey on 525 elderly people over the age of 65 in terms of living habits and eating habits. After that, the elderly who skipped breakfast were four times more likely to develop Alzheimer's than other elderly people.
Skipping breakfast can easily lead to insufficient nutritional intake, which cannot meet the needs of the brain, so that the brain may age prematurely and have the possibility of functional degeneration, which will increase the risk of Alzheimer's disease.
2. Do not eat meat
In the case, Sister Liang was a vegetarian for a long time. During the examination, it was found that the vitamin B12 in her body was 73pg/mL, which was significantly lower than the normal value.
The French National Institute of Health and Medical Research, taking more than 6,000 elderly people over the age of 65 as research objects, found that compared with people who ate meat more than 4 times a week, the risk of Alzheimer's disease in long-term vegetarians was 100%. 67%, and the risk of all types of dementia, including Alzheimer's disease, also reached 58%.
The underlying reason for the increased risk of dementia may be related to vitamin B12 deficiency caused by insufficient meat intake .
4. Measure the risk of dementia
In the case, Ms. Liang's MMSE examination score was 14 points. According to the grading standard of dementia severity , MMSE ≥ 21 is considered mild, MMSE 10-20 is classified as moderate, and MMSE ≤ 9 is classified as severe.
The Mini-Mental State Examination (MMSE) is a widely used clinical cognitive function screening scale, which can be used for preliminary screening of various types of cognitive impairment and dementia. If you suspect this tendency, try it out. Of course, this cannot replace clinical diagnosis.
At present, there is no cure for Alzheimer's disease in the world, but early preventive intervention can still protect the brain's cognitive ability and help delay the occurrence of the disease:
•Strengthen cognitive training, can consciously carry out mental activities
• Lots of fresh fruits and vegetables, deep-sea fish, beans, and some olive oil
•Physical exercise 3-4 times a week, accumulating more than 180 minutes of aerobic exercise per week, preferably combined with strength training
• The risk of dementia should be actively controlled, such as obesity, high blood pressure, diabetes, etc.
The causes of Alzheimer's disease are complex and there is no cure. All we can do is actively intervene to prevent dementia from happening.
References:
[1] "The latest research finds that if the body mass index is maintained at this number, the risk of dementia is the lowest". Medical circles. 2022-05-11
[2] "Disease Day | 10 Signs of Alzheimer's Disease, Parents Should Take Early Prevention If They Have Symptoms". The First Affiliated Hospital of Sun Yat-sen University. 2016-09-21
[3] "Studies have found that if you have this habit of getting up early, the risk of Alzheimer's disease will increase by 4 times! I hope you follow this "brain-building" strategy every day~ ". I am a great doctor. 2022-05-20
[4] What is the evaluation process of the Mini-Mental State Evaluation Examination (MMSE)? ". Psychiatric Nursing. 2022-05-15
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