Gout is 'eat' out? 5 kinds of 'big purines' may increase uric acid, don't be too greedy

Uncle Wang is an old man, and he cooks a pot of old-fashioned soup every day, saying it is to nourish and appetize. But in the past two weeks, Uncle Wang's toes and thumb joints have been repeatedly showing signs of redness, swelling, heat and pain, and even woke up several times in the middle of the night.

The family suspected that it was gout, and asked Uncle Wang to go to the hospital for examination. It was found that Uncle Wang's blood uric acid level was several times higher than the normal value . X-rays showed asymmetric swelling of the first metatarsophalangeal joint. The doctor diagnosed gout.

Uncle Wang felt depressed: I don't drink or smoke, and I don't like seafood very much. How could I get this disease?

During the doctor's careful inquiry, he learned that Uncle Wang likes to drink rich and delicious broth on weekdays . This hobby is most likely one of the important reasons for Uncle Wang's gout.

In fact, in daily life, many people's favorite delicacies are actually "large purine households" that can lead to elevated uric acid.

1. Why is gout more "preferred" to men?

According to the "White Paper on Hyperuricemia and Gout Trends in China" in 2021, the number of hyperuricemia patients in China has reached 177 million , and the number of gout patients has exceeded 14,660, and the majority of patients are male.

Gout is a crystal-related arthropathy caused by the deposition of monosodium urate, which is directly related to hyperuricemia and belongs to the category of metabolic diseases.

Gout can be divided into acute arthritis stage and chronic arthritis stage. Under the incentives of drinking, fatigue, stress, high protein, high purine diet , etc., it can lead to acute gout attack, and patients will feel severe pain in the joints where uric acid is deposited.

Acute gout generally has a self-limiting period and can be relieved on its own within 2 weeks, but this does not mean that patients can be left without treatment and intervention.

If not controlled in time, the patient may face two consequences:

First, during the acute attack , the pain is unbearable and often affects daily activities or sleep at night;

Second, if the treatment is not timely , as the gout progresses, a large number of tophi deposits are deposited in the joints, which can cause joint damage.

Why is gout especially high in men?

Metabolism is carried out in our body every day, and the "garbage" in metabolism includes uric acid, which needs to be regularly transported out of the body by the kidneys and intestines.

When it comes to transporting garbage, androgens are "two hundred and five", which are often intercepted for no reason, preventing the transport process of the intestines and kidneys. Androgens are dominant in males, which greatly reduces the transport efficiency of uric acid waste , making the incidence of males higher than females.

2. Elevated uric acid, the body often has these abnormalities

High uric acid is a precursor to gout. Generally speaking, if the blood uric acid level exceeds 420 micromol/L in men and 360 micromol/L in women, it can be diagnosed as high uric acid.

According to statistics, there are about 200 million people with hyperuricemia in China, and about 12% of them can develop gout . However, when uric acid is elevated, the body will send out warning signals:

1. Joint pain

If the uric acid content is too high, the urate crystals deposit in the form of uric acid stones, which compress the joints and bring pain and swelling to the joints.

2. edema

Excessive uric acid puts a load on the work of the kidneys, and the water in the kidneys is difficult to excrete, and it will accumulate in the body, causing edema.

3. Abnormal urination

Healthy urine is pale yellow and the urination process is smooth and pain-free. If the level of uric acid is high, the urine will become dark and cloudy, which is one of the manifestations of metabolic problems caused by high uric acid.

But in fact, most people have asymptomatic high uric acid, but patients with elevated uric acid do not know it, resulting in the lack of timely dietary and life interventions.

Therefore, it is recommended that people over 60 years old, obese men, postmenopausal women, patients with cardiovascular and cerebrovascular diseases, diabetes patients, patients with kidney stones, people with a family history of gout, people who like to drink and eat meat, it is best to regularly detect blood uric acid levels.

3. Is gout caused by "eating"? 5 foods that may increase uric acid

It seems that in the eyes of most people, gout is caused by "eating", such as various beer, seafood, old fire soup, soy products, etc. In fact, the increase of uric acid is the result of multiple factors.

The influence of uric acid excretion is often related to these three factors: disease, drugs, and personal constitution .

Many people think that uric acid is "eating", but about 20% of uric acid in human blood comes from food, and nearly 80% of the rest is produced by the body's own metabolism.

Most of the exogenous purines in food will be converted and decomposed into uric acid, which can indeed increase the level of blood uric acid, but this is not the main cause of gout. Even strict control of high-purine food intake can only reduce the uric acid value by about 60-120 μmol/L .

However, some foods that people often eat in daily life are actually "big purines", which will accelerate the rise of uric acid and induce gout:

1. Old fire soup

Laohuotang pays attention to time, the longer the time, the better the tonic effect. But in fact, when the meat in the soup is boiled, it will release purine substances. The longer the cooking time, the higher the purine content.

2. Alcohol

Alcohol consumption is a more important risk factor than diet. During the decomposition process, ethanol can lead to the increase of adenosine, a precursor of uric acid, and secondly, it will also increase the level of blood lactate and inhibit the excretion of uric acid. According to national rheumatology statistics, drinking is the main cause of gout in men, up to 25.5%.

3. Seasoning

Food seasonings such as oyster sauce, abalone sauce, hoisin sauce, and mushroom sauce are also high in purine content. They are condiments extracted and concentrated from animals and seafood as raw materials, which also affect the level of uric acid.

4. Foods high in fructose

Fructose is a monosaccharide that can inhibit the excretion of uric acid by the kidneys. Whether a large amount of fructose is ingested at one time or a long-term intake of a large amount of fructose, it can cause blood uric acid to rise.

5. Seafood and offal

Seafood and animal offal are high-level foods in the high-purine food list, and the purine content is generally higher than 150 mg/100 g, especially processed broth, canned, barbecued foods, etc., and the intake should be reduced.

In addition to the taboos to prevent and control gout, it is more important to adhere to the treatment. The purpose of treatment is to control uric acid at a reasonable level and help the body metabolize "garbage" as soon as possible. Food is only an aid, and drug control can help better control .

It is actually not difficult to control the uric acid value within a reasonable range. In life, you should establish a reasonable diet, exercise more, control your weight, and take medicine scientifically. As long as you stick to it, don’t worry about the day when gout comes.

References:

[1] "There is a kind of pain that makes people say goodbye to beer and seafood, its name is gout". Nutshell. 2021-09-01

[2] "Asymptomatic high uric acid is more "dangerous"! Don't let the kidneys suffer silently anymore". Life Times. 2021-06-03

[3] "Rely on this "food purine table" to get the daily diet of gout patients! 》.Medical Endocrinology Channel.2020-06-03

Reproduction is prohibited without the author's permission