The man's uric acid was 820, and he died of uremia. 5 symptoms appeared. Beware that the uric acid has exceeded the standard
Uncle Li from Guangzhou likes to drink wine on weekdays, and likes to take seafood as a drink.
A few days ago, Uncle Li suddenly felt a pain in his thumb while eating with his friends, but he didn't pay much attention to it, thinking it was just a common gout attack. But for a few days in a row, Uncle Li felt that his urination continued to decrease, or even had no urine , so he went to the hospital for examination at the urging of his wife.
During the physical examination, the patient's hands were severely deformed, covered with large and small gout stones, and the bones had been eroded.
The examination found that the patient 's uric acid reached 820μmol/L , and the serum creatinine was as high as 700umol/, indicating that the renal function was significantly damaged and had reached the condition of uremia, while the serum potassium was 6.8mmol/L , and there was a risk of cardiac arrest at any time!
The doctor immediately opened a green channel for Uncle Li, took potassium-lowering treatment and started emergency hemodialysis , but Uncle Li still failed to survive and died at the age of 41.
1. How can high uric acid affect the kidneys?
Uric acid in the body is generated from purine substances in the nucleus, and 80% of the uric acid in the blood comes from the metabolism of its own cells , and the remaining 20% comes from food.
90% of uric acid in the body is excreted through the kidneys , and the remaining 10% is excreted through the intestines.
Hyperuricemia may occur when there is excess uric acid production, impaired uric acid excretion, or both.
The renal function indicators in the examination include serum creatinine, blood uric acid and blood urea nitrogen. The "three items of renal function" can already indicate that renal function is closely related to blood uric acid.
Usually, excessive uric acid will be deposited in the joints, as well as in the renal tubule, renal interstitium and ureter , which can cause renal tubular damage, interstitial nephritis and uric acid nephrolithiasis. If not treated in time, it is likely to further develop into kidney failure.
Various reasons of renal failure will in turn affect the excretion of uric acid and further increase the uric acid value. In clinical cases, some patients strictly control their diet, and the reason for the gradual increase in serum uric acid may be related to the failure to control renal failure .
The importance of uric acid control is obvious. What symptoms appear that may indicate that your uric acid value exceeds the standard?
2. Several manifestations appear, your uric acid may have exceeded the standard
High uric acid is always related to gout, so when you mention high uric acid, you can think of the symptom of joint pain. In fact, if you have the following symptoms, it can also mean that your uric acid exceeds the standard!
Gout: The fingers and toes are prone to redness, swelling, heat and pain, and the pain is like a knife cut.
Joint pain: When uric acid is too high, urate crystals can deposit in the joints, causing joint pain.
Body edema: High uric acid can easily stimulate the kidneys, which hinders the excretion of water from the kidneys, and then manifests as body edema.
Abnormal urination: Excessive uric acid damages the kidneys and causes abnormal metabolism, eventually resulting in darkened or even cloudy urine,
Dry mouth: uric acid needs a lot of water when it passes through the kidneys and is excreted with urine, especially at night when blood flow slows down. When uric acid is high, more uric acid crystals are easily precipitated, resulting in water shortage in the body, manifested as dry mouth , thirst, drinking a lot of water is also difficult to relieve.
Not everyone will experience unpleasant symptoms , which are more dangerous and require regular testing.
In particular, people such as smoking and drinking, lack of exercise, high mental stress, irregular life, high purine diet, staying up late and tired, three highs, cardiovascular disease, kidney disease, and menopausal women should be alert to hyperuricemia.
3. Controlling uric acid, diet control alone is not enough
Although many people believe that hyperuricemia is caused by poor eating habits, this makes sense, but taboos alone are not enough. Control uric acid, you need to do this.
1. Control your diet
"Keep your mouth shut" is the first step, a table of food purine content, eat it in comparison.
In addition, pay attention to four diets :
• Reduce calorie intake and avoid high-calorie, high-fat, high-protein diets;
• Adhere to a low-salt diet, with a daily salt intake not exceeding 6g;
• Stay away from alcohol, especially if you have an acute attack of gout, chronic gouty arthritis, or poor medication control;
• Ensure the daily water intake. Drinking more water and urinating can increase the excretion of uric acid from the body. Generally, the daily water intake should reach 2000ml;
2. Scientific medicine
Patients with hyperuricemia need to actively control high-risk factors such as three highs and chronic kidney disease, and truthfully inform the doctor of their condition when seeking medical treatment, so that the doctor can avoid the use of drugs that will increase blood uric acid according to the situation.
3. Pay attention to the details of life
Generally, the dissolution of uric acid will increase in a warm environment, while the precipitation of uric acid will be promoted in a cold environment. Therefore, when the temperature difference between inside and outside is large in summer, you should pay attention to keeping warm and cover the quilt at night.
In addition, people with high uric acid can take more aerobic exercises such as walking, square dancing or Tai Chi. Note that exercise should not be too strenuous, and do what you can.
4. Pay attention to 5 uric acid indicators
These 5 uric acid indicators are multiples of 60, which are easy to remember.
① For patients with tophi symptoms, uric acid needs to be controlled below 300 μmol.
② For patients without tophi, uric acid needs to be controlled below 360 μmol.
③Under normal circumstances, when uric acid is controlled within 420μmol, it is a normal state.
④If the uric acid in young people reaches 480μmol, the general diet can be controlled, and no special treatment is required.
⑤ When the uric acid value reaches 540 μmol, measures should be taken to control the uric acid level regardless of symptoms.
Today, the number of patients with hyperuricemia is far higher than the number of patients with blood sugar, becoming a veritable "fourth highest". In order to control uric acid, this requires us to develop healthy living habits, while avoiding a large intake of high-purine foods, preferably taking medicines under the guidance of a doctor.
References:
[1] "The truth of gout: Strict taboos, why does uric acid not drop but rise? ". Medical Endocrinology Channel. 2021-07-30
[2] "High uric acid, why some people have unbearable pain, and some people have no symptoms? Don't be careless in these situations...". Popular Science China. 2022-04-10
[3] "Is high uric acid from eating? Many people have misunderstood! There may be problems in these places...". Popular Science China. 2022-01-10
[4] "Asymptomatic high uric acid is more "dangerous"! Don't let the kidneys suffer silently anymore". Life Times. 2021-06-03
[5] "Hot pot + beer, can't gout patients touch it? Experts from West China: Remember 5 Numbers, Eat When You Want". Endocrinology Channel of the Medical Community. 2021-12-16
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