Uremia is 'dragged' out? Reminder: There are 4 symptoms on the skin, it may be that the kidneys are calling for help

Ms. Li (pseudonym) is 35 years old this year and is a middle and senior manager of a private company. During the company's physical examination last month, it was found that the serum creatinine was high, and the report suggested a re-examination, but due to her busy work, she never took time to come.

Recently, she felt very tired, weak when she got up, slight edema in her ankles, and nausea and vomiting. Seeing this, her husband took her to the hospital for treatment.

After examination, the doctor said that Ms. Li's renal function was only 30% left, and the result of renal biopsy indicated IgA nephropathy, renal tubular atrophy and fibrosis, which was already in the early stage of uremia . If it is delayed any longer, he will have to rely on dialysis to maintain his life.

Ms. Li said helplessly, "In recent years, every time I have a physical examination, I have urine protein 1+~2+ and urine occult blood 2+, but because I have no symptoms, I don't care about it. Now it's too late to regret it ."

In recent years, more and more young people suffer from uremia. According to the survey, about 40% of Chinese uremia patients are young people .

1. The majority of uremia is dragged out step by step

Nephrologist Gao Chan said that the early symptoms of kidney disease are relatively hidden and have few specific manifestations , which makes it difficult to detect the disease at an early stage. When obvious symptoms appear, the kidney damage may be irreversible. Once the diagnosis is confirmed, it is kidney failure or even uremia. disease. These early symptoms include weak positive urine protein, mild edema, foamy urine, etc. Many people think it is normal and do not seek medical treatment, which makes the condition worse and worse.

Uremia is not formed overnight. It has three stages of development . If it can be taken seriously and treated early, it can effectively delay the development of the disease and avoid the step of " uremia ".

1. Early

Early kidney disease mainly manifests as hematuria, proteinuria and hypertension. Treatment at this time has the highest probability of cure.

2. Mid-term

If the disease is not well controlled in the early stage, it will develop in the middle stage. At this time, the main manifestations are the increase of blood creatinine and the decline of kidney function. If treatment is available at this time, there is still hope for a cure.

3. Late period

If the disease is allowed to develop, it will lead to end-stage renal disease, which is uremia. At this time, the patient's serum creatinine rises significantly, and the edema is severe. It can also cause gastrointestinal symptoms and skin damage symptoms, which may be accompanied by anemia, high phosphorus, low calcium, and osteoporosis. It can be said that the whole body has been affected.

2. If you have 4 skin symptoms, you should pay attention to whether it is kidney disease.

Skin lesions are a common complication of end-stage renal disease and can seriously affect quality of life. If the following 4 symptoms appear on the skin, it is necessary to suspect the possibility of kidney disease.

1. Skin itching

The most common skin symptom of uremic pruritus occurs in about 15% to 49% of patients, and the incidence rate of dialysis patients is as high as 50% to 90%. This itching typically occurs on the forearms and upper back, and its incidence increases as the condition progresses.

2. Pigmentation

About 25% to 70% of dialysis patients will develop skin pigmentation, tan is more common, especially after sun exposure. Hyperpigmentation increases over time and is more common on the skin of the face and body.

3. Acquired ichthyosis

About 50% to 92% of patients will develop dry skin, and some patients will develop acquired ichthyosis, that is, dry skin with white, gray or brown ichthyosis-like scales.

4. Skin surface crystallization

If uremia patients are not dialyzed in time, the urea concentration in their sweat will greatly increase. After the sweat evaporates, the urea remains on the skin surface and forms a powder, which is called urea cream.

3. For the sake of kidney health, these habits should not be adhered to

Bad living habits can damage the kidneys. For the health of the kidneys, please get rid of these kidney-damaging habits!

Habit 1. Overtired

Excessive fatigue is one of the main risk factors for kidney disease. In the state of excessive fatigue and nervous tension, people's resistance decreases, which may lead to repeated infections for a long time , causing upper respiratory tract infection, eyelid edema, leg swelling, increased blood pressure, etc., and increased damage to the kidneys.

Habit 2. Abuse of folk remedies

Many people are keen on folk remedies and secret remedies, but they do not have strict quality standards, and the added ingredients and dosage are not clear, which not only affects the prognosis of patients, but may also have liver toxicity and nephrotoxicity, which can accelerate the deterioration of kidney disease.

Habit 3. High-purine diet

After purine is metabolized by the liver, it becomes uric acid, 1/3 of which is excreted by the intestines, and 2/3 is excreted by the kidneys.

If you often eat a high-purine diet, the uric acid level will be too high, and it will be stored in the body before it is excreted, which will increase the burden on the kidneys and cause kidney damage. Once the kidney is damaged, its excretory function will further decline, and it will be more difficult to excrete uric acid. The two interact with each other, forming a vicious circle, which will accelerate the deterioration of kidney disease.

Habit 4. Smoking

Harmful substances such as nicotine, lead, and cadmium in cigarettes are nephrotoxic , which can increase blood pressure , damage endothelial cells and glomeruli, and cause kidney disease. The more you smoke, the higher your risk of kidney disease.

4. People with poor kidneys should eat less of one kind of fruit

Lin Sammart, deputy chief physician of the Nephrology Department of Shanghai Hospital of Integrated Traditional Chinese and Western Medicine, said that people with poor kidneys should try not to eat carambola , because carambola is nephrotoxic, and eating it by mistake may cause acute renal failure or poisoning.

In addition, bananas, oranges, peaches, apricots, grapefruit and other potassium-rich fruits should not be taken too much. Dr. Lin recommends that patients with kidney disease can eat some mulberries appropriately . Not only does it not contain high sugar content, but it also contains low potassium content, which is more friendly to the kidneys.

Uremia not only affects the kidneys, but also affects the nervous, cardiovascular, gastrointestinal, blood, respiratory, skin and endocrine systems of the whole body, and can lead to death in severe cases. Nowadays, there are more and more uremias. We must develop good living habits and don't let the kidneys be too injured.

References:

[1] Eight common skin manifestations in patients with kidney disease, how many do you know? , Yimaitong Kidney Channel, 2018-04-24

[2] Niu Qingyu, Zhao Huiping. Research progress of carambola poisoning in patients with chronic kidney disease [J]. Chinese Blood Purification, 2018, 17(6):5.

[3] Yan Xinyi. Research progress of skin damage in chronic kidney disease [J]. International Journal of Urology, 2022, 42(2):3.

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