Will the uric acid exceed the standard? Doesn't uric acid have gout? the doctor tells you
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Plus what is the normal value of uric acid, this is the "three questions of the soul" about blood uric acid!
Many people know that the normal value of uric acid is that it should not exceed 420 μmol/L (7mg/dl), but it will cause gout to be very complicated, because some people are particularly uric acid, no gout occurs, and some of them, and some of them, and some Patients, blood uric acid is normal, but also gout, today we will talk about this problem.
02
The pathological basis of gout seizures is hyperuric hematicmia!
Under normal circumstances, the results of the same patient twice, non -the same day, and an empty stomach measurement can be diagnosed as hyperuricemia if they exceed 420. Measurement of 3 to 5 days, this value will be more accurate.
If our blood uric acid exceeds the normal value, then these excessive blood uric acid is in a saturated state, and uric acid crystals may be formed. These crystals are the culprit that causes gout attacks. They can deposit most of the body's body. Site, including ears, including bone marrow can be deposited. A small amount of uric acid deposition may not induce special problems, but these deposited uric acid crystals will become more and more. When their power is strong enough, riots may be initiated, causing patients to cause patients A gout attack.
However, it does not mean that with hyperuricemia, it will definitely develop into gout. Generally, the higher the possibility of gout in uric acid, the longer the uric acid will exceed the standard, and the greater the possibility of gout. Studies have shown that if blood uric acid exceeds 600, 70.2 among 1,000 people will have the possibility of gout. Over time, if uric acid continues to exceed 600, the possibility of gout will reach 30.5%.
So is it because the blood uric acid exceeds the standard, and there is no gout, everything can be fine, and the blood uric acid is ignored? Of course not, the current research has proven that long -term high uric acid state will cause many other physical damage to patients. For example, each of our blood uric acid increases by 60, it will increase the risk of hypertension 1.4 times, which will be 1.4 times. It will increase the risk of diabetes by 17%, and will lead to a 12% increase in mortality in patients who already have coronary heart disease.
In addition, many patients are now in the state of clinical gout, which means that although the patient has not had gout, but due to the increase in long -term blood uric acid, the patient's joints have caused damage. Bone is damaged, but patients have no symptoms. Hematology is higher than normal for a long time, and it will also increase the possibility of kidney stones.
Generally speaking, even if a patient with hyperuricemia does not have gout, it is in a state of hyperuricemia for a long time, and it is undoubted to the body. It is absolutely necessary to control uric acid.
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Will gout develop in gout patients with normal uric acid control?
If a patient with gout patients is particularly good, the chance of gout seizures will often decrease significantly. When the blood uric acid drops to less than 360, gout recurrence will be less than 14%. But please note that this is not 100%without recurrence, because gout patients still have the crystallization of uric acid in the body. Sometimes it may not be a dietary factor to induce the occurrence of gout. If the rest is not good, it may also lead to the onset of gout.
In addition, there is another possibility that the uric acid has been normal, but gout will recur repeatedly, that is, the crystal dissolution phenomenon that occurs in gout patients during the period of drug lowering uric acid. This phenomenon is very easy to occur in the early stage of uric acid control in gout patients. The main reason is that there are a large number of urate crystals in the patient's body. During the period of reducing uric acid through drugs, the concentration of uric acid in the blood will drop significantly, so the body will By default, the blood uric acid is reduced, and these uric acid crystals will be mobilized to dissolve into the blood, so it is easy to cause the attack of gout. This phenomenon is called the crystal dissolution phenomenon. Onset, the pain tends to be slightly less.
In response to this situation, the minimum dose of uric acid should be used to control uric acid in the early stage of using drugs to reduce uric acid, and the uric acid should be gradually reduced to normal without being too hasty. Narcissine to help control possible inflammatory reactions.
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Hyperuricemia and gout, what kind of situation should be treated with uric acid lowering?
●If the patient's blood uric acid is relatively high, but there is no gout attack. In this case, we usually choose the timing of uric acid-lowering therapy with or without comorbidities. If the patient has hypertension, stroke, coronary heart disease, cardiac insufficiency, uric acid nephrolithiasis, diabetes and other comorbidities, and serum uric acid exceeds 480, uric acid-lowering therapy should be considered, and the target uric acid value should be 360; If there is no comorbidity, uric acid lowering therapy should be performed if it exceeds 540, and the target uric acid value can be reduced to 420.
●If the patient has developed gout and has no comorbidities, uric acid lowering therapy should be performed if the uric acid is higher than 480, and the goal is to reduce it to 360. If the patient has developed gout and has comorbidities, such as two or more gout attacks per year, tophi, chronic gouty arthritis, kidney stones, hypertension, diabetes, dyslipidemia, uric acid higher than 420 Serum uric acid treatment should be performed, and the target uric acid value should be 300.
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Specific measures to lower uric acid!
Patients with hyperuricemia or gout need lifestyle intervention and dietary intervention. In daily life, try to choose ingredients with low purine and purine content, and pay attention to cooking methods, do not choose salt and oil content High cooking methods are more likely to cause abnormal uric acid. In daily life, it is necessary to drink more water, more than 2000 ml per day, and to increase the intake of eggs, milk, ingredients rich in vitamin C and vegetables can help reduce blood uric acid. Try not to drink alcohol, and do not drink more fructose-containing drinks.
In daily life, you should also insist on exercising, such as brisk walking, jogging, swimming, cycling, and yoga, which are more soothing exercises, which are more suitable for gout patients.
● specific drug selection. The choice of drugs for gout patients is very particular. To check which type of patients belong to, there are abnormal uric acid, such as uric acid excretion disorder, or increasing uric acid synthesis, or the common role of the two. Based on the basis The patient’s liver and kidney function and other related tests to choose which drug is more suitable for a patient, so the choice of drugs must be selected with the help of a professional rheumatologist or an endocrinologist. You can take whatever medicine your gout patients take, which is risky.
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Summarize
The problems of acidemia and gout are too common now. The number of people with hyperuricemia in our country has exceeded 170 million, and the number of gout patients has exceeded 17 million. It has become a social problem.
Faced with this problem, everyone must not take it lightly. You must regularly review your blood uric acid and monitor your uric acid status. Even if there is no special abnormality in your body, you should insist on a physical examination every six months to see if your blood uric acid is high. If you are high, you should discover your own problems in time, take timely interventions through lifestyle, and try not to control blood uric acid by means of drugs.
If the blood uric acid is too high or gout has already occurred, you should actively carry out drug control and lifestyle intervention according to the standards in the text, and try to avoid the harm caused by hyperuricemia and gout to the body. If you have other doubts You can leave a message below and let's discuss together.
I am Xie Xinhui, who insists on explaining the knowledge of complex diseases in simple language. It is not easy to code words. If you agree with my point of view, please help to follow or like it. If you or your family and friends are also troubled in this regard, please Forward this article to friends who need it, thank you!