Hypoglycemic drugs emerge in an endless stream, but why is metformin so hard to beat? What are its advantages? One article popular science
Type 2 diabetes patients should have heard of a drug, it is: metformin!
It has to be said that with the high incidence of diabetes, there are more and more clinical researches on hypoglycemic drugs, and new hypoglycemic drugs are constantly coming out.
However, the status of metformin has not been shaken. It is still the first-line drug for the treatment of type 2 diabetes, and it is also the core hypoglycemic drug. If there is a battle for the C position of hypoglycemic drugs, then metformin is the real C position!
Many patients blindly believe that the status of metformin is difficult to shake because its low price is more popular, and it has certain feelings, not its effect.
But in fact, although metformin has an advantage in price, it is not feelings and prices that really conquer patients. According to the content of the "China Guidelines for the Prevention and Treatment of Type 2 Diabetes", metformin is the first-line treatment for patients with 2-star diabetes.
So the question is, what are the advantages of metformin compared with other hypoglycemic drugs?
1. Good effect
In fact, metformin itself is a small molecule drug with very good hydrophilicity. Relevant studies have shown that the basis of metformin's effect on blood sugar is very complex. After taking it, it can not only improve the sensitivity of the patient's body to insulin, relieve insulin Resist symptoms, but also improve the patient's blood sugar tolerance . Moreover, metformin can also reduce postprandial basal blood sugar;
2. Very high security
From research to marketing, metformin has undergone very complex clinical research and clinical trials. And its clinical application time is relatively long, and the clinical experience is very rich.
And, more importantly, metformin is the first and only oral drug approved by the United States and the European Union for use in adolescents with type 2 diabetes over the age of 10.
Its applicable population has expanded from middle-aged and elderly to teenagers. Not only that, but even gestational diabetes patients can also take the drug for treatment, which shows that it is extremely safe. Compared with other hypoglycemic drugs that have just been marketed, metformin has naturally become the best choice.
In fact, the drug metformin is not only very effective in lowering blood sugar. There are also related research investigations that show that metformin tablets can balance the level of glycated hemoglobin in patients, which can reduce the risk index of cardiovascular and cerebrovascular diseases in patients with diabetes in the future .
You know, nearly 1/2 of diabetic patients die because of cardiovascular and cerebrovascular diseases. After reducing the risk of cardiovascular and cerebrovascular diseases, it will undoubtedly be of great help to the future quality of life of patients;
In addition, metformin is very suitable for people with type 2 diabetes, especially those who are obese . Because metformin tablets can play a role in assisting weight loss, it can increase the sensitivity of cells to insulin and reduce fat synthesis . At the same time, it can also regulate the intestinal flora, make the intestinal tract more smooth , and effectively prevent the occurrence of constipation.
In recent years, related studies have confirmed that metformin has many miraculous effects such as anti-aging, preventing Alzheimer's disease, and reducing the risk of cancer. However, its fundamental role is still to lower blood sugar, prevent and treat type 2 diabetes.
Therefore, when doctors suggest that patients choose metformin for treatment, there is no need to worry too much. Following the doctor's advice and arrangements is the first thing to do.