What should I do if the antihypertensive drugs are stopped for a period of time and then taken again, and the effect becomes worse? Teach you 3 steps to troubleshoot the cause

For hypertensive patients, in many cases, long-term antihypertensive drugs are required to control blood pressure levels. In the process of taking antihypertensive drugs, friends often have various problems. For example, a friend asked such a question: the antihypertensive drugs that were originally taken have been discontinued for a period of time. If they are taken again, will the antihypertensive drugs still be effective?

For this problem, for the current mainstream types of antihypertensive drugs, after taking the antihypertensive drugs for a period of time and continuing to take them, the antihypertensive drugs still have antihypertensive effects. Antihypertensive drugs control blood pressure through various principles, such as calcium channel antagonists, which can dilate arteries and lower blood pressure by controlling the intracellular flow of calcium ions; Inhibits the renin-angiotensin-aldosterone system to dilate blood vessels and lower blood pressure. β-blockers can improve the problem of high blood pressure by slowing down the heart rate. Diuretics improve water and sodium retention. Adjusted to lower blood volume to lower blood pressure.

But no matter what type of antihypertensive drugs, there is no such thing as stopping the drug and then taking it again. The effect of the drug will cause the failure of its blood pressure regulating mechanism. Generally speaking, antihypertensive drugs do not have the problem of drug resistance, nor do they There is a problem of taking the same drug again after a period of discontinuation.

If the blood pressure control effect of the antihypertensive drug you originally took is good, the body tolerates it well, and there are no intolerable adverse reactions, no matter what the reason is to stop the drug, if you need to take antihypertensive drugs again, if There is no new health change in the body. It is a relatively safe way to still use the original antihypertensive drug regimen and continue to take the original drug and dosage. Usually, the antihypertensive effect can be guaranteed, and the safety of the drug is also guaranteed. Don't worry too much.

In real life, there may be such a situation. It turns out that taking a kind of antihypertensive drug has a good effect on blood pressure control, and the safety is also good. If this happens, don't rush to a conclusion. You might as well use the following 3 steps to confirm the possible reasons for the failure of antihypertensive drugs.

Step 1: Eat for a while and see

At present, many antihypertensive drugs are long-acting antihypertensive drugs. Long-acting antihypertensive drugs have a long effect in the body, stable pressure control, and convenient medication. It is one of the basic principles of antihypertensive selection for patients with hypertension. However, long-acting antihypertensive drugs also have a disadvantage, that is, it often takes a period of time to achieve a stable blood drug concentration and achieve a better blood pressure control effect. Therefore, if the drugs you re-take are long-acting antihypertensive drugs, such as most of the prilin drugs, all sartans, amlodipines, etc., if you find that the antihypertensive effect is not effective a few days before you resume the drug Well, don't rush to change the medicine first, you might as well take it for a while to see, usually after 2 to 4 weeks, the antihypertensive effect of antihypertensive drugs can reach a stable state. In this case, the blood pressure of hypertensive patients is often , is under control.

Step 2: Confirm the life conditioning intervention for hypertension

If you take antihypertensive drugs again and find that the antihypertensive effect is not as good as before, you should not ask yourself, apart from taking the medicine, how big is the change in your lifestyle? It turned out that when I was taking the medicine, if I strictly controlled salt in my diet, I usually paid attention to exercise, quit smoking, limit alcohol, and didn’t stay up late. Blood pressure is naturally not well controlled. Only strict self-discipline life conditioning intervention, supplemented by drugs for high blood pressure control, can better and more stable control of blood pressure levels.

Step 3: Appropriately adjust the antihypertensive drug regimen according to your physical condition

If the above two situations are achieved, you can be strictly self-disciplined in life and take medicine for a long time, but the effect of lowering blood pressure is still unsatisfactory. Generally, you should consider whether the blood pressure status of the body has changed, or whether there are other Disease problems have caused further increase in blood pressure. For such a situation, it is recommended to seek medical attention for proper diagnosis and adjust the drug regimen according to the actual situation. If the original drug has a certain effect and there is no drug contraindication, it can be used in the original drug. On the basis, the combination of medication should be used to strengthen blood pressure control. If the blood pressure is secondary to elevated due to other diseases, the focus should be on strengthening the control of related diseases, and at the same time, attention should be paid to adjusting the medication regimen and strengthening the regulation of blood pressure.