Cephalosporin with wine and go away? In addition to not drinking after taking medicine, do not touch alcohol in these 4 situations!
Everyone must have heard this sentence in daily life: cephalosporins are paired with wine, and you can leave!
Many people disagree with this, because in our opinion, cephalosporin is nothing more than an antibiotic for the treatment of diseases. However, the fact that cephalosporins and alcohol may cause death is not an alarmist, because the combination of the two may cause a disulfiram reaction!
Disulfiram itself is a drug used to get rid of alcohol addiction. After taking this drug, even if you drink a small amount of alcohol, the body will have a serious discomfort reaction, and then it will play a role in quitting drinking.
When alcohol and cephalosporin are taken together, a disulfiram reaction occurs . That is to say, after ethanol enters the body, it can be metabolized into acetaldehyde, but the secretion of acetaldehyde dehydrogenase is inhibited, acetaldehyde cannot be decomposed and metabolized , and begins to accumulate in the body, and then a series of uncomfortable symptoms appear.
Mild patients may manifest as red face, conjunctival congestion, blurred vision, dizziness, headache, nausea and vomiting and other drunken symptoms. Severe patients may experience problems such as chest tightness, shortness of breath, sweaty taste, myocardial infarction, heart failure, dyspnea, acute liver damage , and even death . Therefore, it is not recommended to drink alcohol after taking medicine.
In fact, in addition to not drinking after taking medication, the following conditions are not suitable for drinking:
1. Drinking blush
In fact, most Chinese people have acetaldehyde dehydrogenase gene defects. This gene defect will not affect physical health, but it will slow down the metabolism of alcohol .
Ethanol is metabolized into acetaldehyde, but acetaldehyde cannot be quickly metabolized and decomposed, so even if a small amount of alcohol is consumed, such people will experience blushing symptoms. This is not a sign of being able to drink, but a signal of alcoholism . Therefore, for this group of people, alcohol consumption should be avoided;
2. Have liver disease
The liver is the main site of alcohol metabolism and degradation. In the process of alcohol metabolism, ethanol and acetaldehyde will directly cause liver cell damage and inhibit other biotransformation capabilities of the liver .
Even in people without liver disease, long-term heavy drinking may lead to alcoholic liver disease. Therefore, for patients who have suffered from alcoholic liver disease, fatty liver, hepatitis, etc., they should avoid drinking alcohol;
3. Cardiovascular and cerebrovascular diseases
If you have problems such as high blood pressure and atherosclerosis, it is not suitable to drink alcohol. Because alcohol has the effect of dilating blood vessels after entering the body.
Blood pressure seems to drop in a short period of time, but it increases the blood pumping burden of the heart. After alcohol is metabolized, blood pressure will rebound and rise again . In this case, it may cause vasospasm and contraction, unstable plaques fall off and form thrombosis , or even induce serious diseases such as stroke and myocardial infarction;
4. Pregnant women, breastfeeding
A large number of studies have shown that alcohol has certain harm to the fetus. It can affect the normal development of the fetus through the placenta , and even has the risk of teratogenicity. Not only that, a lot of alcohol abuse during pregnancy may also cause miscarriage, premature birth, fetal growth retardation and other problems , so you should avoid drinking alcohol during pregnancy.
In addition, it is not suitable for women to drink a lot during breastfeeding, because alcohol may enter the body of young children through breast milk, which will seriously affect the growth and development of the baby, especially the development of cranial nerves.
In fact, alcohol is a substance that is harmful to the human body without any benefit. Everyone should clearly understand the harm of alcohol, especially the above categories of people should not drink alcohol.
Even healthy people are better off completely abstaining from alcohol. If you cannot stop drinking, it is necessary to appropriately reduce the amount of drinking and control the frequency of drinking.