Cephalosporin is paired with wine, just go! In addition to cephalosporins, don't touch alcohol with these 5 drugs. Are you taking them?

Between husband and wife or couples, it is inevitable that there will be quarrels and discord, but a couple had a fight before, but they wanted to take cefplus wine at the same time to commit suicide.

It turned out that Ms. Bai and her boyfriend had been in love for many years. After a fierce argument one day, Ms. Bai's boyfriend took the cephalosporin and alcohol and left, so scared that Ms. Bai hurriedly called the police.

After the police contacted Ms. Bai's boyfriend, they found that he had taken a relatively small dose, and he was not in serious trouble. Before the police could breathe a sigh of relief, Ms. Bai also took cephalosporins. Fortunately, both of them were not in danger in the end.

1. Why can't cephalosporins be paired with wine?

Many people are familiar with the saying "Cefs go with wine, go away", so why can't cephalosporins be paired with wine?

Taking cephalosporin and alcohol at the same time can cause disulfiram-like reactions, which can seriously endanger life . Cephalosporin contains tetrazolium side chain. If taken with alcohol, acetaldehyde cannot be oxidized and accumulates in the body. After half an hour, dizziness, nausea, fever, vomiting, dyspnea, chest pain may occur. , Disulfiram -like symptoms such as incontinence .

2. Why are some people okay with cephalosporin and wine?

Some people will scoff when they hear cephalosporins paired with alcohol and leave, thinking that they are fine with cephalosporins and alcohol, and they do not experience some of the above-mentioned similar symptoms.

In fact, not all cephalosporins will produce disulfiram-like reactions. Drugs such as cefotaxime and cefpirin do not contain tetrazolium side chains, and disulfiram-like reactions will not occur. If the dose happens to be small and the body has a good metabolism, there may be asymptomatic phenomena, but for the sake of life, it is recommended not to take cephalosporins and alcohol-containing things at the same time.

Third, these drugs can not be touched with alcohol

In addition to cephalosporins that cannot be taken with alcohol, the following drugs cannot be taken with alcohol at the same time.

1. Sedative and hypnotic drugs

Sedative and hypnotic drugs generally include phenobarbital, diazepam, chloral hydrate, chlordiazepoxide, etc. These drugs generally inhibit the brain. Once taken with alcohol at the same time, ethanol will accelerate the absorption of the drug, resulting in excessive drug concentration in the body. high, resulting in mild or severe poisoning.

2. Antipyretic analgesics

Antipyretic and analgesic drugs such as paracetamol and aspirin generally contain caffeine. Once they encounter alcohol, they may damage the gastrointestinal mucosa, causing symptoms such as gastric ulcers, gastritis, and gastric bleeding, and may also lead to cardiac arrhythmias. Symptoms such as rapid heartbeat appear.

3. Antihypertensive drugs

Antihypertensive drugs such as captopril, reserpine, nifedipine, etc., taken at the same time as alcohol may cause tyramine to not be destroyed and accumulate in the body, causing dizziness, diarrhea, nausea, arrhythmia, and severe hypotension , some symptoms of shock, etc.

4. Hypoglycemic drugs

Antidiabetic drugs such as metformin, glyburide, insulin, etc., are not suitable to be taken at the same time as alcohol. If you just finished taking hypoglycemic drugs, your blood sugar will slowly drop to the standard value, and once you drink alcohol, it may lead to an increase in insulin secretion, which may induce hypoglycemia, and may even cause symptoms such as lactic acidosis.

5. Anti-arthritis drugs

Drugs for treating arthritis such as methotrexate cannot be taken at the same time as alcohol. Once both are taken at the same time, it is likely to cause some negative effects such as gastric bleeding, gastric ulcer, and liver damage.

During the period of taking cephalosporins, you can not drink alcohol. The encounter between the two is likely to cause a disulfiram-like reaction. Although some people may be fine with cephalosporins and alcohol, for safety reasons, it is better not to take these two things at the same time. There are also many drugs that cannot be taken at the same time as alcohol.

References:

[1] "Cefs just drink, just leave"? Danger! Don't drink alcohol while taking these drugs... Popular Science China. 2021-02-15

[2] "Cefpo with wine, just leave"? Notice! Drinking can "take away" you and these medicines! .Zhengzhou Central Hospital Affiliated to Zhengzhou University.2020-06-03

[3] Eating cephalosporins and drinking alcohol will kill you! This article tells you what to do, pay attention to these types of drugs and be careful.... China Medical Tribune. 2021-10-05

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