Cephalos with wine, just leave! In addition to cephalosporins, don't touch alcohol with these 5 medicines, are you taking them?

Between husband and wife or lovers, it is inevitable that there will be times of quarrel and discord, but there was a couple who quarreled before, but they wanted to take cephalosporin and wine at the same time to commit suicide.

It turned out that Ms. Bai and her boyfriend had been in love for many years. After a fierce quarrel one day, Ms. Bai's boyfriend took cephalosporin and alcohol and left. Ms. Bai was so frightened that she quickly called the police.

After the police contacted Ms. Bai's boyfriend, they found out that he had taken a relatively small dose and he was fine. Before the police could breathe a sigh of relief, Ms. Bai also took cephalosporins. Fortunately, neither of them was in danger in the end.

1. Why can't cephalosporin be paired with wine?

Many people are familiar with the saying "ceph is wine, go away as soon as you say it", so why can't cephalosporin be paired with wine?

Taking cephalosporin and alcohol at the same time will cause a disulfiram-like reaction, which may seriously endanger life safety . Cephalosporin contains the side chain of methionine tetrazole. If taken together with alcohol, acetaldehyde cannot be oxidized and accumulates in the body. After about half an hour, dizziness, nausea, fever, vomiting, dyspnea, and chest pain may occur. , incontinence and other disulfiram-like symptoms.

2. Why is it okay for some people to drink cephalosporin with wine?

Some people will scoff when they hear that cephalosporin is paired with wine, and they will go away as soon as they say, thinking that they are fine with cephalosporin paired with wine, and they have not experienced some of the above-mentioned similar symptoms.

In fact, not all cephalosporins will produce disulfiram-like reactions. Drugs such as cephalothin and cefapirin do not contain tetrazole side chains, and disulfiram-like reactions will not occur. If the dose happens to be small and the body metabolism is good, there may be asymptomatic phenomena, but for the sake of life, it is recommended not to take cephalosporins and alcoholic things at the same time.

3. These drugs should not be mixed with alcohol

In addition to cephalosporins that cannot be taken with alcohol at the same time, the following drugs cannot be taken with alcohol at the same time.

1. Sedative and hypnotic drugs

Sedative and hypnotic drugs generally include phenobarbital, diazepam, chloral hydrate, chlordiazepoxide, etc. These drugs generally inhibit the brain. Once taken together with alcohol, ethanol will accelerate the absorption of the drug, resulting in excessive drug concentration in the body. High, resulting in mild or severe poisoning reactions.

2. Antipyretic analgesics

Antipyretic and analgesic drugs such as paracetamol and aspirin generally contain caffeine. Once it meets alcohol, it may damage the gastrointestinal mucosa, cause symptoms such as gastric ulcer, gastritis, and gastric bleeding, and may also lead to tachycardia. Rapid, rapid heartbeat and other symptoms.

3. Antihypertensive drugs

Antihypertensive drugs such as captopril, reserpine, and nifedipine, taken together with alcohol may cause tyramine to be unable to be destroyed and accumulate in the body in large quantities, causing dizziness, diarrhea, nausea, arrhythmia, and severe hypotension , Shock and other symptoms.

4. Hypoglycemic drugs

Hypoglycemic drugs such as metformin, glibenclamide, and insulin are not suitable for taking with alcohol. If you have just finished taking hypoglycemic drugs, your blood sugar will slowly drop to the standard value, and once you drink alcohol, it may lead to increased insulin secretion, thereby inducing hypoglycemia, and even symptoms such as lactic acidosis.

5. Arthritis drugs

Drugs for arthritis such as methotrexate should not be taken with alcohol at the same time. Once the two are taken at the same time, it is likely to cause some negative effects such as gastric bleeding, gastric ulcer, and liver damage.

During the period of taking cephalosporins, you can not drink alcohol. The encounter between the two is likely to cause a disulfiram-like reaction. Although some people may be fine with cephalosporins with alcohol, for safety reasons, it is better not to take these two things at the same time. Usually There are also many drugs that should not be taken with alcohol.

References:

[1] "The cephalosporin is drinking, just leave if you say it"? Danger! Do not drink alcohol while taking these drugs.... Popular Science China.2021-02-15

[2] "Pair cephalosporin with wine, just leave"? Notice! Drinking can take you "out" and these pills! .Zhengzhou Central Hospital Affiliated to Zhengzhou University.2020-06-03

[3] Eating cephalosporins and drinking alcohol will kill you! This article tells you what to do, pay attention to these types of drugs and be careful.... China Medical Tribune. 2021-10-05

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